The CD2v protein enhances African swine fever virus replication in the tick vector, Ornithodoros erraticus

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African Swine Fever Virus Strain Georgia 2007/1 in Ornithodoros erraticus Ticks

3. Department of Health. United Kingdom. Chapter 25: pneumococcal. In: Immunisation against infectious diseases—‘The green book’. 2006 [cited 2011 Nov 11]. http://www.dh.gov.uk/PolicyAndGuidance/HealthAndSocialCareTopics/GreenBook/GreenBookGeneralInformation/ GreenBookGeneralArticle/fs/en?CONTENT_ ID=4097254&chk=isTfGX) 4. Borrow R, Stanford E, Waight P, Helbert M, Balmer P, Warrington R, et al...

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1. European Food Safety Authority. EFSA Panel on Animal Health and Welfare; scientifi c opinion on African swine fever. EFSA Journal. 2010;8:1556. http://dx.doi. org/10.2903/j.efsa.20101556 2. Sanchez-Botija C. Reservoirs of ASFV: a study of the ASFV in arthropods by means of the haemadsorption test. Bull Off Int Epizoot. 1963;60:895–9. 3. Boinas FS, Wilson AJ, Hutchings GH, Martins C, Dixon LJ...

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The CD2v protein of African swine fever virus interacts with the actin-binding adaptor protein SH3P7.

The predicted extracellular domain of the CD2v protein of African swine fever virus (ASFV) shares significant similarity to that of the CD2 protein in T cells but has a unique cytoplasmic domain of unknown function. Here we have shown that CD2v is expressed as a glycoprotein of approximately 105 kDa in ASFV-infected cells. In the absence of an extracellular ligand, the majority of CD2v appears ...

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The Persistence of African Swine Fever Virus in Field-Infected Ornithodoros erraticus during the ASF Endemic Period in Portugal

African swine fever (ASF) is an important disease of pigs and outbreaks of ASF have occurred in Europe on multiple occasions. To explore the period for which the European soft tick species Ornithodoros erraticus (Acari: Argasidae) is able to act as a reservoir of African swine fever virus (ASFV) after infected hosts are removed, we collected specimens from farms in the provinces of Alentejo and...

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African swine fever virus replication in the midgut epithelium is required for infection of Ornithodoros ticks.

Although the Malawi Lil20/1 (MAL) strain of African swine fever virus (ASFV) was isolated from Ornithodoros sp. ticks, our attempts to experimentally infect ticks by feeding them this strain failed. Ten different collections of Ornithodorus porcinus porcinus ticks and one collection of O. porcinus domesticus ticks were orally exposed to a high titer of MAL. At 3 weeks postinoculation (p.i.), <2...

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ژورنال

عنوان ژورنال: Virology

سال: 2009

ISSN: 0042-6822

DOI: 10.1016/j.virol.2009.07.040